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Betulinic Acid ≥98% | CAS 472-15-1 | Pharma/Cosmetic Use

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Betulinic Acid ≥98% | CAS 472-15-1 | Pharma/Cosmetic Use

Betulinic Acid ≥98% | CAS 472-15-1 | Pharma/Cosmetic Use

Betulinic Acid (CAS 472-15-1) is a naturally occurring pentacyclic triterpenoid compound, primarily extracted from birch bark (Betula spp.) and other plant sources. With the molecular formula C??H??O? and a molecular weight of 456.71, it appears as a white to off-white crystalline powder. This bioactive compound is renowned for its broad-spectrum pharmacological properties.

  • Product Name :

    Betulinic Acid
  • CAS No. :

    472-15-1
  • Appearance :

    Fine White Powder
  • Specification :

    98%

?? Betulinic Acid (Pentacyclic Triterpene from Betula alba Bark)

CAS No.: 472-15-1
Molecular Formula: C??H??O?
Molecular Weight: 456.7


?? Technical Specifications

Parameter Detail
Purity Range ≥98% (HPLC)
Identification HPLC-DAD, ¹H/¹³C-NMR
Solubility Soluble in DMSO, chloroform; insoluble in water (0.0002 g/L at 25°C)
Melting Point 256-258°C
Optical Rotation +8° (c=1, CHCl?)
Storage 2-8°C (vacuum-sealed, amber glass; avoid light)
Shelf Life 24 months

?? Industry-Specific Applications

Industry Use Cases
Pharmaceuticals - Targeted melanoma therapeutics
- Adjuvant for chemo-radiotherapy sensitization
Cosmeceuticals - Anti-acne serums 
- Collagen-boosting anti-aging creams
Nutraceuticals - Liver detox supplements
- Metabolic syndrome support
Veterinary - Canine melanoma topical formulations
- Livestock antiviral feed additives

?? Competitive Advantages

  • Selective Cytotoxicity: Kills cancer cells 20x more effectively than normal cells.

  • Dual Sourcing: Sustainable extraction from Betula alba bark (FSC-certified) or Syzygium claviflorum leaves.

  • Bioenhanced Forms: β-cyclodextrin complexes available (water solubility ↑ 300x).


?? Packaging & Storage

  • Bulk: 1 kg/vacuum aluminum cans with oxygen scavenger.

  • Samples: 100 mg, 500 mg in argon-purged glass vials.

  • Storage: Stable 2 years at 2-8°C; avoid freeze-thaw cycles (>5 cycles degrade purity by 0.8%).


?? Why Choose Betulinic Acid?

  1. Mechanism-Backed Efficacy:

    • Triggers mitochondrial pore formation (VDAC activation).

  2. Supply Chain Transparency:

    • Traceable from European birch forests (Batch-specific GPS coordinates).

  3. Formulation Support:

    • Preclinical data packages for IND applications.

  4. Regulatory Readiness:

    • DMF Type II filed (US FDA); REACH/ISO 9001certified.

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